Differences in Cardioprotective Efficacy of Adrenergic Receptor Antagonists and Ca 21 Channel Antagonists in an Animal Model of Dilated Cardiomyopathy
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چکیده
(Fz-DCM). whether five cardioactive agents were cardioprotective in this model of heart failure, ie, they prevented dilatation and wall thinning and improved contractile performance. We compared the effects of chronic administration of af,3-selective and a nonselective 3-receptor antagonist, a-receptor antagonist, two Ca2' channel antagonists in the presence of Fz administration. The greatest cardioprotection was found with treatment with either propranolol or nifedipine. the gross
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تاریخ انتشار 2005